|
KMID : 1094020230400050387
|
|
Journal of Veterinary Clinics
2023 Volume.40 No. 5 p.387 ~ p.392
|
|
|
A Case of Visceral T Cell Lymphoma with Prominent Histiocyte Infiltration in a Dog
|
|
Kim Myung-Chul
Go Du-Min
Woo Sang-Ho
Oh Jeong-Seop
Kim Dae-Yong
Kim Na-Yon
Lee Soon-Ho
Jung Jae-Ha
Youn Hwa-Young
Kim Yong-Baek
|
|
|
Abstract
|
|
|
|
A 13-year-old intact male English Springer Spaniel presented with anorexia. Physical examination revealed a palpable abdominal mass without peripheral lymphadenopathy. Ultrasonography revealed hepatosplenomegaly and a markedly enlarged hepatic lymph node. Fine-needle aspiration of the splenic and nodal lesions revealed atypical round cells admixed with numerous histiocytes. The dog was euthanized owing to deteriorating condition despite a month of chemotherapy with lomustine. Histopathology revealed obliteration of the normal architecture of the liver, spleen, kidney, and hepatic and mesenteric lymph nodes by CD3+ neoplastic lymphocytes, accompanied by extensive F4/80+ histiocytic infiltration. This report describes a rare presentation of T-cell lymphoma with prominent histiocytic infiltration that may initially be misdiagnosed as histiocytic neoplasia in a dog.
|
|
|
KEYWORD
|
|
|
case report, fine needle aspiration, histiocyte, T cell lymphoma, visceral involvement
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|